De sykdomsmodifiserende legemidlene brukes gjerne i kombinasjon med symptomlindrende legemidler som betennelsesdempende- og smertestillende legemidler.Som nevnt så er det ofte slik at vi spenner oss ekstra i muskler og at smertefibre blir mer sensitive når vi har kronisk smertesyndrom.Kristoffersen fant også at kun tre prosent av de med kronisk
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